Effects of Bright Light on Cognitive and Sleep-Wake (circadian) Rhythm Disturbances in
Alzheimer-type Dementia. Psychiatry and Clinical Neurosciences 2000; 54(3):352-3
Hiroshi Yamadera, Takao Ito, Hideaki Suzuki, Kentaro Asayama, Ritsuko Ito, Shunkichi Endo.
"These results suggest that bright light therapy improved the circadian rhythm disturbances and then bettered the cognitive state in early-stage ATD (Alzheimer-type dementia)." Abstract
Sleep Rhythm Disturbances in Alzheimer's Disease (Article in French)
Revue Med Interne 2003;24(3):165-71
F Onen, SH Onen.
"Sleep-wake rhythm disturbances observed in Alzheimer's disease are correlated with the severity of cognitive impairment and often result in institutionalization. These disturbances are also a major cause of psychotropic medication misuse."
"In Alzheimer patients, controlling sleep-wake disturbances with sedative drugs often increases both sleep disturbance and cognitive dysfunction. A chronobiological approach with bright-light therapy, melatonin administration, restricted time in bed, and diurnal activity may be an interesting therapeutic alternative in the management of sleep-wake disorders in Alzheimer patients. The aim of these therapeutics is to improve sleep and diurnal activity and consequently to increase the quality of life in Alzheimer patients." Abstract